COVID-19 information and resources for the public on precautions to avoid illness, vaccines, symptoms, testing, treatments, and therapeutics.

Precautions to Avoid Illness

Feeling Sick?

  • Fever or chills

  • Cough

  • Shortness of breath or difficulty breathing

  • Fatigue

  • Muscle or body aches

  • Headache

  • New loss of taste or smell

  • Sore throat

  • Congestion or runny nose

  • Nausea or vomiting

  • Diarrhea



If you have COVID-19, you can spread the virus to others. Isolation and avoiding contact with people who are at high risk of getting very sick can help prevent others from getting sick.

Treatments and Therapeutics

The U.S. Food and Drug Administration issued an Emergency Use Authorization to allow the use of monoclonal antibodies for the treatment of mild to moderate symptoms of COVID-19 in adults and pediatric patients.

View the South Dakota Monoclonal Antibody Treatment flyer

What are monoclonal antibodies? Monoclonal antibodies are laboratory-made proteins that mimic the antibodies created by your immune system to fight off harmful viruses. Bamlanivimab + etesevimab and casirivimab + imdevimab are monoclonal antibodies that are specifically designed to protect against severe COVID-19 infection. The antibodies bind to the spike protein of the COVID-19 virus to stop the virus from entering your cells and continuing the infection.

  • Who can get this treatment? Antibody treatment can be used by people with mild to moderate COVID-19 who:
    • Test positive for SARS-CoV-2;
    • Are within 10 days of the start of their symptoms;
    • Are age 12 or older and weigh at least 88 pounds; and
    • Are at high risk of progressing to severe COVID-19 infection or of needing to be admitted to a hospital because of COVID-19. Examples of chronic medical conditions include:
      • Chronic kidney disease
      • Diabetes
      • Immunosuppressive disease
      • Currently receiving immunosuppressive treatment
      • Having a body mass index (BMI) greater than 25 (overweight or obese)
      • Pregnancy
      • Aged 65 years and older
      • Cardiovascular disease (including congenital heart disease) or hypertension
      • Chronic lung diseases (e.g., chronic obstructive pulmonary disease [COPD], asthma [moderate-to-severe], interstitial lung disease, cystic fibrosis, and pulmonary hypertension)
      • Sickle cell disease
      • Neurodevelopmental disorders (e.g., cerebral palsy) or other complex conditions (e.g., genetic or metabolic syndromes and severe congenital abnormalities)
      • Having a medical-related technological dependence (e.g, tracheostomy, gastrostomy, or positive pressure ventilation [not related to COVID-19])

Individuals who meet high-risk criteria and test positive should contact their primary care physician about a referral for antibody treatment within three days of a positive test result and no later than 10 days after symptom onset.

Treatment for COVID-19 is available in many parts of the state. Check with your healthcare provider about the use of monoclonal antibodies or an antiviral.

COVID-19 Monoclonal Antibody Therapeutics Locations

Avera Health
  • Avera St. Luke’s Hospital - Aberdeen
  • Avera Dells Area Hospital - Dell Rapids
  • Avera De Smet Memorial Hospital - De Smet
  • Avera Flandreau Hospital - Flandreau
  • Freeman Regional Hospital - Freeman
  • Avera Gregory Hospital - Gregory
  • Avera Milbank Area Hospital - Milbank
  • Avera Hand Co. Memorial Hospital - Miller
  • Avera Queen of Peace Hospital - Mitchell
  • Avera St Benedict Hospital - Parkston
  • Avera St. Mary’s Hospital - Pierre
  • Avera Platte Health Center - Platte
  • Community Memorial Hospital - Redfield
  • Avera Landmann-Jungman Memorial Hospital - Scotland
  • Avera St. Michael’s Hospital -Tyndall
  • Avera Wagner Community Hospital - Wagner
  • Avera Sacred Heart Hospital - Yankton
Monument Health
  • Monument Health Custer Hospital - Custer
  • Monument Health Lead-Deadwood Hospital - Deadwood
  • Philip Health Services - Philip
  • Monument Health Rapid City Hospital - Rapid City
  • Monument Health Spearfish Hospital - Spearfish
  • Monument Health Sturgis Hospital - Sturgis
Sanford Health
  • Sanford Aberdeen Medical Center - Aberdeen
  • Douglas Co Memorial Hospital - Armour
  • Community Memorial Hospital - Burke
  • Sanford Canton-Inwood Medical Center - Canton
  • Sanford Chamberlain Medical Center - Chamberlain
  • Sanford Clear Lake Medical Center - Clear Lake
  • Sanford USD Medical Center - Sioux Falls
  • Sanford Vermillion Medical Center - Vermillion
  • Pioneer Memorial Hospital - Viborg
  • Sanford Webster Medical Center - Webster
  • Winner Regional Hospital - Winner
Independent Hospitals
  • Bowdle Hospital - Bowdle
  • Brookings Health System – Brookings
  • Faulkton Area Medical Center - Faulkton
  • Fall River Health Services - Hot Springs
  • Huron Regional Healthcare Center - Huron
  • Madison Community Hospital - Madison
  • Bennett Co Hospital - Martin
  • Mobridge Regional Hospital - Mobridge
  • Oyate Health Center - Rapid City
  • Prairie Lakes Healthcare System - Watertown