The Youth Tobacco Survey (YTS) began in 1997 to assess the prevalence of tobacco use and examine factors that contribute to tobacco use among school-age youth. Data from the YTS serves to enhance the capacity of state agencies and organizations to design, implement, and evaluate tobacco prevention and control programs. South Dakota (SD) began statewide youth tobacco surveillance in 2003 using the South Dakota Youth Tobacco Survey (SD YTS). The SD YTS is an adaptation of the national YTS and includes state-added questions specific to programming and youth tobacco use trends in SD. After the 2003 baseline survey, the SD YTS was repeated biannually from 2005 to 2019, providing valuable data to track tobacco use trends among youth.