Hand, Foot & Mouth Disease

Hand, Foot, & Mouth Disease is a viral illness caused by several different viruses from the enterovirus group that inhabit the human intestinal tract. Man is the only known source for this illness. Foot and Mouth disease of cattle, sheep and swine is not communicable to man. Another virus of domestic animals (called ORF virus) is communicable to man, but causes lesions only on the skin.

Disease Fact Sheet

Disease Facts

Anyone can get Hand, Foot, & Mouth disease. Man is the only known source for these viruses. Because there are several different viruses that cause the same syndrome, seemingly, a person can get the illness more than once.

By direct contact with nose and throat discharges and feces of infected persons. Virus is also present in the blister-like lesions.

Some persons experience sudden onset of fever and sore throat along with small, discrete grayish-white lesions ("sores"). These lesions may be present on any of the soft tissue inside the mouth. Some persons experience lesions that are raised and/or blister-like on the body, most notably the palms, fingers and the soles of the feet. These lesions may persist for 7-10 days.

Usually lesions appear 3-5 days after exposure.

A person can be considered infectious during the time symptoms are present. These viruses inhabit the human intestinal tract and may persist in stool for several weeks, even after symptoms disappear.

Diagnosis is based mainly on clinical symptoms. Virus may be isolated from lesions, nasopharyngeal or stool specimens. Since many viruses may produce the same syndrome, these tests are not routinely done.

There is no specific treatment. Viral illnesses in general are self-limiting, meaning, you will get over the illness without outside influence. There are some medications available to temporarily ease the discomfort from the lesions. Complications are rare and there are no fatalities associated with this disease.

Reduce person-to-person contact where practicable, such as avoiding crowded gatherings or poorly ventilated areas. Good personal hygiene is important in preventing spread - especially hand-washing after passing stool, contact with nose and throat discharges or articles soiled therewith.


This material is provided by the South Dakota Department of Health for informational purposes only and is not a substitute for medical care. We are not able to answer personal medical questions. Please see your health care provider concerning appropriate care, treatment, or other medical advice.

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